R&D pipeline

A wide range of alkylthiolated products is accessible through nucleophilic substitution reactions, both on aromatic and aliphatic substrates, or using conjugated nucleophilic addition reactions (1,2 addition).

3-(METHYLSULFANYL)PROPANOIC ACID

IUPAC name: 3-(methylsulfanyl)propanoic acid
Other names: 3-(methylthio)propionic acid
CAS 646-01-5 - EC 211-460-9

Intermediate used in the synthesis of suplatast tosilate

Molecular formula

1-[4-(METHYLSULFANYL)PHENYL]ETHAN-1-ONE

IUPAC name: 1-[4-(methylsulfanyl)phenyl]ethan-1-one
Other names: (4’-methylthio)acetophenone, 1-(p-tolyl)ethanethione, 4'-(Methylmercapto)acetophenone
CAS 1778-09-2 - EC 217-213-1

Intermediate used in the synthesis of elafibranor and rofecoxib

Molecular formula

4-(METHYLSULFANYL)BENZALDEHYDE

IUPAC name: 4-(methylsulfanyl)benzaldehyde
Other name: 4-(methylthio)benzaldehyde, p-Methylthiobenzaldehyde, 4-(Mercaptomethyl)benzaldehyde
CAS 3446-89-7 - EC 222-365-7

Intermediate used in the synthesis of etoricoxib, exisulind, florfenicol, polmacoxib, saroglitazar, sulindac and thiamphenicol

Molecular formula

4-N-ETHYL-6-METHYLSULFANYL-2-N-PROPAN-2-YL-1,3,5-TRIAZINE-2,4-DIAMINE

IUPAC name: 4-N-ethyl-6-methylsulfanyl-2-N-propan-2-yl-1,3,5-triazine-2,4-diamine
Other names: ametryn
CAS 834-12-8 - EC 212-634-7

Example of industrial scale use of alkylthiolation technology.

Molecular formula

6-METHYLSULFANYL-2-N,4-N-DI(PROPAN-2-YL)-1,3,5-TRIAZINE-2,4-DIAMINE

IUPAC name: 6-methylsulfanyl-2-N,4-N-di(propan-2-yl)-1,3,5-triazine-2,4-diamine
Other names: prometryn
CAS 7287-19-6 - EC 230-711-3

Example of industrial scale use of alkylthiolation technology.

Molecular formula